The Purification Insights Blog

Ten things you must know when producing synthetic therapeutic peptides

Posted by The Bio-Works Team on Nov 18, 2019 9:40:39 AM
The Bio-Works Team
Find me on:

Peptide therapeutic agents are enjoying increasing success but they are challenging to produce and, not least, to purify. Purity requirements are, in fact, approaching those for small molecules. Synthesis generates a challenging crude mixture containing failed sequences and chemical variants. 

 

We asked an expert

We asked a seasoned industry expert who currently works in this area and who has more than 35 years experience in chromatography, including the resin business, drug discovery, scaling-up and GMP production of biological pharmaceuticals:

  • How do you best plan and carry out a purification process for a synthetic therapeutic peptide?
  • What are the most critical and fundamental factors to focus on and where do most processes, or people, go wrong?

Ten peptide purification tips cropped

It's all summarized in ten points and nine pages

The answers are summarized in the nine-page guide that you can download for free at the bottom of this page.

Is this your first time setting up a protocol and you want to avoid the most ridiculous mistakes at least? 

Do you know it all already? Or are there a few things you've forgotten about?

Get it right from the start, do a sanity check on your standard thinking or get a nice training list to hand out to your colleagues... whatever your interest, we hope you'll find something useful here.

Download it now!

Download the peptide purification guide

 

 

 

All product and company names marked with ™ are trademarks or registered trademarks of Bio-Works or of the respective trademark holders. Use by Bio-Works of trademarks of other holders does not imply any affiliation with or endorsement by them.

Posted by The Bio-Works Team

The Bio-Works staff are seasoned and enthusiastic (yes, even a bit nerdy) experts in purification resins, methods and strategies with many years of experience of the ins and outs of this field. We love our job and we’d love to help you do yours by sharing some good solid facts, principles and best practice. In short – “purification made simple”.

LinkedIn Google+

Website

Topics: Tips and Tricks, Biologics, Biopharmaceuticals, Peptides, Peptide drugs, orthogonal, synthetic peptides

GET SOME PURIFICATION WISDOM

...and simplify your life

Managing purification protocols is never easy. So, Bio-Works’ experts have got together to provide our best inspiration and tips - whether you’re just starting up or already on the way to the next, satisfying success.

We’ll share all our best knowledge and hard-earned insights.
Here you’ll find:

  • Comprehensive overviews
  • Short focus articles on method details
  • Tips and tricks to smooth out wrinkles

It’s simple, just subscribe here and start collecting purification wisdom, for free!

Subscribe Here!

Recent Posts