The Purification Insights Blog

QuickTip #2: choosing IEX resin

Posted by The Bio-Works Team on Sep 12, 2019 11:55:00 AM
The Bio-Works Team
Find me on:

Recovery of the biological activity of your target substance is a priority, and it’s important to check for its pH and ionic strength stability values...

Bio-Works chromatography  QuickTips

As long as your target substance is stable over a wide pH range above and below the pI, you can use either an anion (e.g. Q or DEAE) or a cation exchanger (e.g. S). Otherwise, use a cation exchanger if your target is most stable below its pI and an anion exchanger if it is most stable above its pI.

 

Posted by The Bio-Works Team

The Bio-Works staff are seasoned and enthusiastic (yes, even a bit nerdy) experts in purification resins, methods and strategies with many years of experience of the ins and outs of this field. We love our job and we’d love to help you do yours by sharing some good solid facts, principles and best practice. In short – “purification made simple”.

LinkedIn Google+

Website

Topics: Quick Tips, Tips and Tricks, Ion exchange chromatography, IEX

GET SOME PURIFICATION WISDOM

...and simplify your life

Managing purification protocols is never easy. So, Bio-Works’ experts have got together to provide our best inspiration and tips - whether you’re just starting up or already on the way to the next, satisfying success.

We’ll share all our best knowledge and hard-earned insights.
Here you’ll find:

  • Comprehensive overviews
  • Short focus articles on method details
  • Tips and tricks to smooth out wrinkles

It’s simple, just subscribe here and start collecting purification wisdom, for free!

Subscribe Here!

Recent Posts