The Purification Insights Blog

Optimizing mAb purification using a guard column

Posted by The Bio-Works Team on Feb 11, 2019 4:11:57 PM

What are the benefits of introducing multimodal ion exchange chromatography as a guard column and could they include a significant increase in mAb purity? This article presents a study in which two protein A affinity chromatography resins were compared to see whether the introduction of a guard column could improve mAb purity and to discover which of the protein A resins produced the best results.

 

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Topics: mAbs, Ion exchange chromatography, guard column, Multimodal, WorkBeads TREN

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