The Purification Insights Blog

Improved peptide purification promises to boost process efficiency in the race to affordable insulin in China

Posted by The Bio-Works Team on May 29, 2019 9:57:45 AM

The global diabetes pandemic has created a massive demand for insulin, especially in China, which is expected to soon have half the world’s diabetes patients. Meeting this demand means developing extremely efficient production methods that can supply affordable insulin with high purity. A promising approach is to add an orthogonal step upstream the main reverse-phase chromatography (RPC) peptide purification to increase purity and also guard the expensive high-performance RPC columns from bioburden and stringent cleaning-in-place procedures.

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Topics: Biopharmaceuticals, Peptides, Peptide drugs, Cleaning in place, Resin fouling, RPC

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